|
Synonyms :
|
Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF
|
|
Description :
|
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
|
|
Catalog #:
|
100-16A
|
|
Source :
|
E.coli
|
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses.
|
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per ug (1EU/µg).
|
|
Biological Activity :
|
The ED 50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
|
|
Selected References :
|
Selected List of References Citing This Product
|
|
AA Sequence :
|
VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
|
|
PubMed Link :
|
TGFalpha
|
|
Country of Origin :
|
USA
|
|
|
|
|
|
|
Size A
|
20µg
|
$80
|
|
|
|
|
Size B
|
100µg
|
$195
|
|
|
|
|
Size C
|
1mg
|
$1100
|
|
|
|
|
|
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.
|
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
手机网站
