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Synonyms :
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none.
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Description :
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Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
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Catalog #:
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120-12
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED 50 is 0.01–0.04 μg/ml in the presence of 50 ng/ml Myostatin.
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AA Sequence :
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MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
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PubMed Link :
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Myostatin+AND+Propeptide
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Country of Origin :
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USA
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Size A
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5µg
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$80
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Size B
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25µg
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$195
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Size C
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1mg
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$5200
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Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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